Can you take Quercetin and Vitamin C together?
They regenerate each other's antioxidant capacity. Vitamin C restores spent quercetin to its active form, and quercetin protects Vitamin C from oxidation.
Severity
Info
Evidence
moderate
Timing
Together with food.
How it works
Ascorbic acid reduces oxidised quercetin back to its active form; quercetin reciprocally inhibits Vitamin C oxidation.
The synergistic antioxidant effect exceeds what either provides alone. Many quercetin supplements include Vitamin C for this reason. Both are water-soluble, though quercetin absorbs better with fat.
What to do
Take together. Quercetin absorbs better with a fat-containing meal. Vitamin C has no fat requirement but benefits from being taken alongside quercetin.
Frequently asked
Should I separate Quercetin and Vitamin C?
This is an informational interaction. Quercetin and Vitamin C are generally fine to take together. Vitamin C recycles oxidised quercetin
Why do Quercetin and Vitamin C interact?
Ascorbic acid reduces oxidised quercetin back to its active form; quercetin reciprocally inhibits Vitamin C oxidation.
How strong is the evidence for this interaction?
The evidence is moderate. Some studies support this interaction, but more research may be needed.
About these supplements
Other Quercetin interactions
Other Vitamin C interactions
Check your full stack
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See what competes, what combines well, and when to take everything. Every interaction cites a published source.
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1 flagZinc and Iron compete for the same absorption pathway. Take at least 2 hours apart.
Supplements
This information is for educational purposes only. It is not medical advice and does not diagnose, treat, cure, or prevent any disease. Always consult a qualified healthcare professional.