Blog

Research, guides, and updates on supplement interactions, timing, and stack management.

TimingApril 16, 2026

Fat-soluble vs water-soluble vitamins: when to take what

Your vitamins fall into two groups with different absorption rules, storage behaviour, and timing requirements. Here's how to stop taking them wrong.

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InteractionsApril 15, 2026

Melatonin and magnesium: stacking for sleep

Melatonin handles your circadian signal. Magnesium supports GABA and muscle relaxation. Together, they're one of the most common sleep stacks. Dosing, timing, and what the research says about combining them.

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GuidesApril 9, 2026

What a sleep stack looks like (and what to skip)

Magnesium, melatonin, L-theanine, glycine, apigenin. The internet has opinions on all of them. Here's what the research actually supports for sleep, and what's mostly marketing.

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InteractionsApril 8, 2026

Ashwagandha and thyroid medication: what the research says

Ashwagandha can raise T3 and T4 levels. If you take levothyroxine or other thyroid medication, this interaction is clinically meaningful. Here's what the research shows and when to talk to your doctor.

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Deep DiveApril 2, 2026

Peptides: GHK-Cu, BPC-157, and what the research actually says

Peptides are the fastest-growing category in the supplement space. The claims are bold. The evidence is mostly animal data. Here's what we know, what we don't, and what to watch out for.

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InteractionsApril 1, 2026

Magnesium and calcium: why order matters

Both minerals are essential. Both compete for absorption. Getting the balance and timing right is more important than most people realise.

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InteractionsMarch 25, 2026

Zinc and copper: the ratio nobody talks about

Zinc is one of the most popular supplements. But chronic zinc supplementation without copper can cause a deficiency you never expected. Here's why the ratio matters.

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InteractionsMarch 18, 2026

Vitamin C and iron: does it actually help absorption?

The advice to take vitamin C with iron is everywhere. The mechanism is real: ascorbic acid converts iron to a more absorbable form. But how much does it actually matter?

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InteractionsMarch 11, 2026

Fish oil and vitamin E: the oxidation question

Omega-3 fatty acids are highly prone to oxidation. Vitamin E is a fat-soluble antioxidant. The pairing makes chemical sense, but does the research support it?

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InteractionsMarch 4, 2026

Vitamin D and K2: do you need both?

Vitamin D helps you absorb calcium. Vitamin K2 tells that calcium where to go. Without K2, calcium may end up in the wrong places. Here's what the research actually shows.

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InteractionsFebruary 18, 2026

Magnesium and vitamin D: why they need each other

Vitamin D gets all the attention. But without enough magnesium, your body can't activate it. Here's how the two nutrients depend on each other.

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InteractionsFebruary 18, 2026

Zinc and iron: why timing matters more than you think

Both minerals use the same absorption pathway. Taking them together can cut absorption by up to 50%. Here's what the research says and what you can do about it.

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InteractionsFebruary 17, 2026

Calcium and iron: can you take them together?

Adding milk to your iron-rich meal can cut absorption by half. Calcium is one of the strongest inhibitors of iron uptake, and most people have no idea.

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InteractionsFebruary 16, 2026

Turmeric and black pepper: the 2000% absorption claim

Piperine inhibits glucuronidation, which is how your body clears curcumin. The 2000% bioavailability number is real. But the study behind it is more nuanced than the headline.

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TimingFebruary 15, 2026

Should you take supplements with food or on an empty stomach?

Some supplements need fat. Some need an empty stomach. Some do not care either way. Here is what the absorption research actually says.

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GuidesFebruary 14, 2026

The beginner stack: 5 supplements that actually have evidence

Vitamin D3, magnesium, omega-3, vitamin K2, and creatine. Five supplements with decades of research, widespread deficiency data, and a clear reason to exist. What to take, how much, and when.

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TimingFebruary 13, 2026

Morning vs evening: does supplement timing actually matter?

Magnesium at night, iron in the morning, fat-soluble vitamins with food. Some of this is real. Some is oversimplified. Here's what the absorption research actually says.

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