Can you take Caffeine and Calcium together?
Above 300 mg caffeine daily, there's a small increase in urinary calcium excretion. The effect is easily offset by adequate calcium intake.
Severity
Caution
Evidence
moderate
Timing
No timing issue.
How it works
Caffeine increases renal calcium excretion and may slightly reduce intestinal calcium absorption.
Each cup of coffee causes roughly 5 mg additional calcium loss in urine — easily offset by a tablespoon of milk. The concern is primarily for people combining very high caffeine (>400 mg/day) with low calcium intake.
What to do
No strict timing needed. If you drink more than three cups of coffee daily, make sure your calcium intake is adequate. The interaction is too small to warrant separating supplements.
Frequently asked
Should I separate Caffeine and Calcium?
Consider separating them. No timing issue. Ensure adequate calcium if caffeine is high. Consult a healthcare professional for personalised advice.
Why do Caffeine and Calcium interact?
Caffeine increases renal calcium excretion and may slightly reduce intestinal calcium absorption.
How strong is the evidence for this interaction?
The evidence is moderate. Some studies support this interaction, but more research may be needed.
About these supplements
Other Caffeine interactions
Other Calcium interactions
Related reading
Check your full stack
for interactions.
See what competes, what combines well, and when to take everything. Every interaction cites a published source.
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6 supplements
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1 flagZinc and Iron compete for the same absorption pathway. Take at least 2 hours apart.
Supplements
This information is for educational purposes only. It is not medical advice and does not diagnose, treat, cure, or prevent any disease. Always consult a qualified healthcare professional.