Can you take Curcumin and Black Pepper Extract together?
Piperine from black pepper can increase curcumin bioavailability by approximately 2,000%. Most quality curcumin supplements already include it.
Severity
Info
Evidence
strong
Timing
Together with food.
How it works
Piperine inhibits hepatic and intestinal glucuronidation of curcumin, slowing its metabolic clearance and raising plasma levels.
The landmark Shoba et al. (1998) study used 5 mg piperine, which has become the standard dose. Piperine also affects CYP enzymes that metabolise many drugs, so check with a pharmacist if you take prescription medications.
What to do
Take curcumin with piperine and a fatty meal for maximum absorption. If your curcumin supplement doesn't include piperine, add 5–10 mg from a separate black pepper extract.
Frequently asked
Should I separate Curcumin and Black Pepper Extract?
This is an informational interaction. Curcumin and Black Pepper Extract are generally fine to take together. Piperine dramatically increases curcumin absorption
Why do Curcumin and Black Pepper Extract interact?
Piperine inhibits hepatic and intestinal glucuronidation of curcumin, slowing its metabolic clearance and raising plasma levels.
How strong is the evidence for this interaction?
The evidence is strong, supported by multiple published studies and clinical data.
About these supplements
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Supplements
This information is for educational purposes only. It is not medical advice and does not diagnose, treat, cure, or prevent any disease. Always consult a qualified healthcare professional.